ROLE OF CHIMAERINS, A GROUP OF Rac-SPECIFIC GTPase ACTIVATING PROTEINS, IN T-CELL RECEPTOR SIGNALING

Chimaerins are GTPase-activating proteins that inactivate the GTP-hydrolase Rac1 in a diacylglycerol-dependent manner. To date, the study of chimaerins has been done mostly in neuronal cells. Here, we show that α2- and β2-chimaerin are expressed at different levels in T-cells and that they participa...

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Bibliographic Details
Main Authors: Caloca, María José, Delgado, Pilar, Alarcón, Balbino, Bustelo, Xosé R.
Format: Artigo
Language:Inglês
Published: 2007
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2277368/
https://ncbi.nlm.nih.gov/pubmed/18249095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2007.12.015
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