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An orderly inactivation of intracellular retention signals controls surface expression of the T cell antigen receptor

Exit from the endoplasmic reticulum (ER) is an important checkpoint for proper assembly of multimeric plasma membrane receptors. The six subunits of the T cell receptor (TCR; TCRα, TCRβ, CD3γ, CD3δ, CD3ɛ, and CD3ζ) are each endowed with ER retention/retrieval signals, and regulation of its targeting...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Delgado, Pilar, Alarcón, Balbino
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Rockefeller University Press 2005
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2213059/
https://ncbi.nlm.nih.gov/pubmed/15728236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20041133
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