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An orderly inactivation of intracellular retention signals controls surface expression of the T cell antigen receptor

Exit from the endoplasmic reticulum (ER) is an important checkpoint for proper assembly of multimeric plasma membrane receptors. The six subunits of the T cell receptor (TCR; TCRα, TCRβ, CD3γ, CD3δ, CD3ɛ, and CD3ζ) are each endowed with ER retention/retrieval signals, and regulation of its targeting...

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Bibliografske podrobnosti
Main Authors: Delgado, Pilar, Alarcón, Balbino
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2005
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2213059/
https://ncbi.nlm.nih.gov/pubmed/15728236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20041133
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