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Avidity for antigen shapes clonal dominance in CD8(+) T cell populations specific for persistent DNA viruses

The forces that govern clonal selection during the genesis and maintenance of specific T cell responses are complex, but amenable to decryption by interrogation of constituent clonotypes within the antigen-experienced T cell pools. Here, we used point-mutated peptide–major histocompatibility complex...

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Main Authors: Price, David A., Brenchley, Jason M., Ruff, Laura E., Betts, Michael R., Hill, Brenna J., Roederer, Mario, Koup, Richard A., Migueles, Steven A., Gostick, Emma, Wooldridge, Linda, Sewell, Andrew K., Connors, Mark, Douek, Daniel C.
格式: Artigo
語言:Inglês
出版: The Rockefeller University Press 2005
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212993/
https://ncbi.nlm.nih.gov/pubmed/16287711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20051357
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