Immunologic Pressure within Class I-Restricted Cognate Human Immunodeficiency Virus Epitopes during Highly Active Antiretroviral Therapy

Cytotoxic T lymphocytes (CTL) and highly active antiretroviral therapy (HAART) are known to exert strong evolutionary pressures on the virus population during human immunodeficiency virus (HIV) infection. However, it is not known whether CTL responses continue to substantially affect viral evolution...

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Detalhes bibliográficos
Main Authors: Casazza, Joseph P., Betts, Michael R., Hill, Brenna J., Brenchley, Jason M., Price, David A., Douek, Daniel C., Koup, Richard A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1075692/
https://ncbi.nlm.nih.gov/pubmed/15731259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.6.3653-3663.2005
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