Preferential Infection Shortens the Life Span of Human Immunodeficiency Virus-Specific CD4(+) T Cells In Vivo

CD4(+) T-cell help is essential for effective immune responses to viruses. In human immunodeficiency virus (HIV) infection, CD4(+) T cells specific for HIV are infected by the virus at higher frequencies than other memory CD4(+) T cells. Here, we demonstrate that HIV-specific CD4(+) T cells are bare...

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Main Authors: Brenchley, Jason M., Ruff, Laura E., Casazza, Joseph P., Koup, Richard A., Price, David A., Douek, Daniel C.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2006
Assuntos:
Pathogenesis and Immunity
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1489023/
https://ncbi.nlm.nih.gov/pubmed/16809286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00070-06
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