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Avidity for antigen shapes clonal dominance in CD8(+) T cell populations specific for persistent DNA viruses

The forces that govern clonal selection during the genesis and maintenance of specific T cell responses are complex, but amenable to decryption by interrogation of constituent clonotypes within the antigen-experienced T cell pools. Here, we used point-mutated peptide–major histocompatibility complex...

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Bibliografische gegevens
Hoofdauteurs: Price, David A., Brenchley, Jason M., Ruff, Laura E., Betts, Michael R., Hill, Brenna J., Roederer, Mario, Koup, Richard A., Migueles, Steven A., Gostick, Emma, Wooldridge, Linda, Sewell, Andrew K., Connors, Mark, Douek, Daniel C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Rockefeller University Press 2005
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212993/
https://ncbi.nlm.nih.gov/pubmed/16287711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20051357
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