Acquisition of direct antiviral effector functions by CMV-specific CD4(+) T lymphocytes with cellular maturation

The role of CD4(+) T cells in the control of persistent viral infections beyond the provision of cognate help remains unclear. We used polychromatic flow cytometry to evaluate the production of the cytokines interferon (IFN)-γ, tumor necrosis factor (TNF)-α, and interleukin (IL)-2, the chemokine mac...

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Hlavní autoři: Casazza, Joseph P., Betts, Michael R., Price, David A., Precopio, Melissa L., Ruff, Laura E., Brenchley, Jason M., Hill, Brenna J., Roederer, Mario, Douek, Daniel C., Koup, Richard A.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2006
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Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118179/
https://ncbi.nlm.nih.gov/pubmed/17158960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20052246
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