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Where CD4(+)CD25(+) T reg cells impinge on autoimmune diabetes
Foxp3 is required for the generation and activity of CD4(+)CD25(+) regulatory T (T reg) cells, which are important controllers of autoimmunity, including type-1 diabetes. To determine where T reg cells affect the diabetogenic cascade, we crossed the Foxp3 scurfy mutation, which eliminates T reg cell...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The Rockefeller University Press
2005
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2212985/ https://ncbi.nlm.nih.gov/pubmed/16301745 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20051409 |
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