Thymic output generates a new and diverse TCR repertoire after autologous stem cell transplantation in multiple sclerosis patients

Clinical trials have indicated that autologous hematopoietic stem cell transplantation (HSCT) can persistently suppress inflammatory disease activity in a subset of patients with severe multiple sclerosis (MS), but the mechanism has remained unclear. To understand whether the beneficial effects on t...

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Detalhes bibliográficos
Main Authors: Muraro, Paolo A., Douek, Daniel C., Packer, Amy, Chung, Katherine, Guenaga, Francisco J., Cassiani-Ingoni, Riccardo, Campbell, Catherine, Memon, Sarfraz, Nagle, James W., Hakim, Frances T., Gress, Ronald E., McFarland, Henry F., Burt, Richard K., Martin, Roland
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2005
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212822/
https://ncbi.nlm.nih.gov/pubmed/15738052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20041679
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