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Protein Arginine Deiminase 4: Evidence for a reverse protonation mechanism
The presumed role of an overactive Protein Arginine Deiminase 4 (PAD4) in the pathophysiology of rheumatoid arthritis (RA) suggests that PAD4 inhibitors could be used to treat an underlying cause of RA, potentially offering a mechanism to stop further disease progression. Thus, the development of su...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2007
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2212595/ https://ncbi.nlm.nih.gov/pubmed/17497940 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi700095s |
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