Wild-type but not Alzheimer-mutant amyloid precursor protein confers resistance against p53-mediated apoptosis

Amyloid precursor proteins (APPs) are expressed in multiple organs and cell types in diverse species. Their conservation across species and high abundance in brain and the association of various APP missense mutations with autosomal dominant forms of familial Alzheimer’s disease (FAD) suggest import...

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Detaylı Bibliyografya
Asıl Yazarlar: Xu, Xiao, Yang, Daseng, Wyss-Coray, Tony, Yan, Jim, Gan, Li, Sun, Yi, Mucke, Lennart
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The National Academy of Sciences 1999
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC22123/
https://ncbi.nlm.nih.gov/pubmed/10377452
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