Evidence for Selective Transformation of Autoreactive Immature Plasma Cells in Mice Deficient in Fasl

Germline mutations in Fas and Fasl induce nonmalignant T cell hyperplasia and systemic autoimmunity and also greatly increase the risk of B cell neoplasms. B lymphomas occurring in Fasl mutant (gld) mice usually are immunoglobulin (Ig) isotype switched, secrete Ig, and are plasmacytoid in appearance...

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Hoofdauteurs: Zhang, Jian Qiao, Okumura, Cheryl, McCarty, Thomas, Shin, Min Sun, Mukhopadhyay, Partha, Hori, Mitsuo, Torrey, Ted A., Naghashfar, Zohreh, Zhou, Jeff X., Lee, Chang Hoon, Roopenian, Derry C., Morse, Herbert C., Davidson, Wendy F.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Rockefeller University Press 2004
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2211944/
https://ncbi.nlm.nih.gov/pubmed/15583018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20041575
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