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BAFF and selection of autoreactive B cells

BAFF is a critical survival factor for transitional and mature B cells and is a promising therapeutic target for SLE. A BAFF inhibitor, belimumab, is the first new drug in 50 years to be approved for the treatment of SLE. However, the mechanism of action of this drug is not entirely clear. In this r...

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Bibliografiske detaljer
Main Authors: Liu, Zheng, Davidson, Anne
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3151317/
https://ncbi.nlm.nih.gov/pubmed/21752714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2011.06.004
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