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BAFF and selection of autoreactive B cells

BAFF is a critical survival factor for transitional and mature B cells and is a promising therapeutic target for SLE. A BAFF inhibitor, belimumab, is the first new drug in 50 years to be approved for the treatment of SLE. However, the mechanism of action of this drug is not entirely clear. In this r...

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Detalhes bibliográficos
Main Authors: Liu, Zheng, Davidson, Anne
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3151317/
https://ncbi.nlm.nih.gov/pubmed/21752714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2011.06.004
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