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The Effect of BAFF Inhibition on Autoreactive B-Cell Selection in Murine Systemic Lupus Erythematosus

The goal of this study was to determine how B-cell–activating factor of the TNF family (BAFF) availability influences selection of the autoreactive B-cell repertoire in NZB/W and NZW/BXSB lupus-prone mice bearing the site-directed heavy-chain transgene 3H9 that encodes for anti-dsDNA and anti-cardio...

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Detalhes bibliográficos
Publicado no:Mol Med
Main Authors: Boneparth, Alexis, Woods, Megan, Huang, Weiqing, Akerman, Meredith, Lesser, Martin, Davidson, Anne
Formato: Artigo
Idioma:Inglês
Publicado em: Feinstein Institute for Medical Research 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004722/
https://ncbi.nlm.nih.gov/pubmed/26882090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2016.00022
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