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The Rationale for BAFF Inhibition in Systemic Lupus Erythematosus

BAFF (B-cell–activating factor) is a critical survival factor for transitional and mature B cells and is a promising therapeutic target for systemic lupus erythematosus (SLE). In 2010–2011, two phase 3 clinical trials showed that the addition of the anti-BAFF antibody belimumab to standard-of-care t...

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Detaylı Bibliyografya
Yazar: Davidson, Anne
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3389191/
https://ncbi.nlm.nih.gov/pubmed/22535567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11926-012-0258-2
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