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Ubiquitin-dependent Degradation of p73 Is Inhibited by PML
p73 has been identified recently as a structural and functional homologue of the tumor suppressor p53. Here, we report that p73 stability is directly regulated by the ubiquitin–proteasome pathway. Furthermore, we show that the promyelocytic leukemia (PML) protein modulates p73 half-life by inhibitin...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2211783/ https://ncbi.nlm.nih.gov/pubmed/15184504 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20031943 |
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