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Screening for E3-Ubiquitin ligase inhibitors: challenges and opportunities

The ubiquitin proteasome system (UPS) plays a role in the regulation of most cellular pathways, and its deregulation has been implicated in a wide range of human pathologies that include cancer, neurodegenerative and immunological disorders and viral infections. Targeting the UPS by small molecular...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Oncotarget
Päätekijät: Landré, Vivien, Rotblat, Barak, Melino, Sonia, Bernassola, Francesca, Melino, Gerry
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Impact Journals LLC 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4226663/
https://ncbi.nlm.nih.gov/pubmed/25237759
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