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β-Catenin Is Dispensable for Hematopoiesis and Lymphopoiesis

β-catenin–mediated Wnt signaling has been suggested to be critically involved in hematopoietic stem cell maintenance and development of T and B cells in the immune system. Unexpectedly, here we report that inducible Cre-loxP–mediated inactivation of the β-catenin gene in bone marrow progenitors does...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Cobas, Monica, Wilson, Anne, Ernst, Bettina, Mancini, Stéphane J.C., MacDonald, H. Robson, Kemler, Rolf, Radtke, Freddy
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2211763/
https://ncbi.nlm.nih.gov/pubmed/14718516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20031615
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