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Notch1 Deficiency Dissociates the Intrathymic Development of Dendritic Cells and T Cells

Thymic dendritic cells (DCs) form a discrete subset of bone marrow (BM)-derived cells, the function of which is to mediate negative selection of autoreactive thymocytes. The developmental origin of thymic DCs remains controversial. Although cell transfer studies support a model in which T cells and...

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Autors principals: Radtke, Freddy, Ferrero, Isabel, Wilson, Anne, Lees, Rosemary, Aguet, Michel, MacDonald, H. Robson
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193172/
https://ncbi.nlm.nih.gov/pubmed/10748227
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