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Notch 1–Deficient Common Lymphoid Precursors Adopt a B Cell Fate in the Thymus

We have recently reported that Notch 1, a member of the Notch multigene family, is essential for the development of murine T cells. Using a mouse model in which Notch 1 is inactivated in bone marrow (BM) precursors we have shown that B cells instead of T cells are found in the thymus of BM chimeras....

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Detalhes bibliográficos
Principais autores: Wilson, Anne, MacDonald, H. Robson, Radtke, Freddy
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193487/
https://ncbi.nlm.nih.gov/pubmed/11581321
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