Localization of HIV-1 Vpr to the nuclear envelope: Impact on Vpr functions and virus replication in macrophages

BACKGROUND: HIV-1 Vpr is a dynamic protein that primarily localizes in the nucleus, but a significant fraction is concentrated at the nuclear envelope (NE), supporting an interaction between Vpr and components of the nuclear pore complex, including the nucleoporin hCG1. In the present study, we have...

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Main Authors: Jacquot, Guillaume, Le Rouzic, Erwann, David, Annie, Mazzolini, Julie, Bouchet, Jérôme, Bouaziz, Serge, Niedergang, Florence, Pancino, Gianfranco, Benichou, Serge
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2007
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2211753/
https://ncbi.nlm.nih.gov/pubmed/18039376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-4-84
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