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Localization of HIV-1 Vpr to the nuclear envelope: Impact on Vpr functions and virus replication in macrophages

BACKGROUND: HIV-1 Vpr is a dynamic protein that primarily localizes in the nucleus, but a significant fraction is concentrated at the nuclear envelope (NE), supporting an interaction between Vpr and components of the nuclear pore complex, including the nucleoporin hCG1. In the present study, we have...

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Bibliografske podrobnosti
Main Authors: Jacquot, Guillaume, Le Rouzic, Erwann, David, Annie, Mazzolini, Julie, Bouchet, Jérôme, Bouaziz, Serge, Niedergang, Florence, Pancino, Gianfranco, Benichou, Serge
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2211753/
https://ncbi.nlm.nih.gov/pubmed/18039376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-4-84
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