Influence of Reverse Transcriptase Variants, Drugs, and Vpr on Human Immunodeficiency Virus Type 1 Mutant Frequencies

The evolution of drug resistance is a major complication of human immunodeficiency virus type 1 (HIV-1) chemotherapy. HIV-1 reverse transcriptase (RT) is a major target of antiretroviral therapy and ultimately the target of drug resistance mutations. Previous studies have indicated that drug-resista...

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Hlavní autoři: Mansky, Louis M., Le Rouzic, Erwann, Benichou, Serge, Gajary, Lisa C.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2003
Témata:
Vaccines and Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC140916/
https://ncbi.nlm.nih.gov/pubmed/12525642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.3.2071-2080.2003
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