Localization of HIV-1 Vpr to the nuclear envelope: Impact on Vpr functions and virus replication in macrophages

BACKGROUND: HIV-1 Vpr is a dynamic protein that primarily localizes in the nucleus, but a significant fraction is concentrated at the nuclear envelope (NE), supporting an interaction between Vpr and components of the nuclear pore complex, including the nucleoporin hCG1. In the present study, we have...

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Autori principali: Jacquot, Guillaume, Le Rouzic, Erwann, David, Annie, Mazzolini, Julie, Bouchet, Jérôme, Bouaziz, Serge, Niedergang, Florence, Pancino, Gianfranco, Benichou, Serge
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2007
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2211753/
https://ncbi.nlm.nih.gov/pubmed/18039376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-4-84
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