Characterization of the Molecular Determinants of Primary HIV-1 Vpr Proteins: Impact of the Q65R and R77Q Substitutions on Vpr Functions

Although HIV-1 Vpr displays several functions in vitro, limited information exists concerning their relevance during infection. Here, we characterized Vpr variants isolated from a rapid and a long-term non-progressor (LTNP). Interestingly, vpr alleles isolated from longitudinal samples of the LTNP r...

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Main Authors: Jacquot, Guillaume, Le Rouzic, Erwann, Maidou-Peindara, Priscilla, Maizy, Marion, Lefrère, Jean-Jacques, Daneluzzi, Vincent, Monteiro-Filho, Carlos M. R., Hong, Duanping, Planelles, Vicente, Morand-Joubert, Laurence, Benichou, Serge
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2009
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2759284/
https://ncbi.nlm.nih.gov/pubmed/19838296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007514
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