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A polymer physics perspective on driving forces and mechanisms for protein aggregation

Protein aggregation is a commonly occurring problem in biology. Cells have evolved stress-response mechanisms to cope with problems posed by protein aggregation. Yet, these quality control mechanisms are overwhelmed by chronic aggregation-related stress and the resultant consequences of aggregation...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Pappu, Rohit V., Wang, Xiaoling, Vitalis, Andreas, Crick, Scott L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2211569/
https://ncbi.nlm.nih.gov/pubmed/17931593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2007.08.033
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