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Quantitative Characterization of Intrinsic Disorder in Polyglutamine: Insights from Analysis Based on Polymer Theories

Intrinsically disordered proteins (IDPs) are unfolded under physiological conditions. Here we ask if archetypal IDPs in aqueous milieus are best described as swollen disordered coils in a good solvent or collapsed disordered globules in a poor solvent. To answer this question, we analyzed data from...

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Bibliografische gegevens
Hoofdauteurs: Vitalis, Andreas, Wang, Xiaoling, Pappu, Rohit V.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Biophysical Society 2007
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1959550/
https://ncbi.nlm.nih.gov/pubmed/17526581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.110080
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