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A polymer physics perspective on driving forces and mechanisms for protein aggregation

Protein aggregation is a commonly occurring problem in biology. Cells have evolved stress-response mechanisms to cope with problems posed by protein aggregation. Yet, these quality control mechanisms are overwhelmed by chronic aggregation-related stress and the resultant consequences of aggregation...

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Autores principales: Pappu, Rohit V., Wang, Xiaoling, Vitalis, Andreas, Crick, Scott L.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2211569/
https://ncbi.nlm.nih.gov/pubmed/17931593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2007.08.033
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