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Influence of hPin1 WW N-terminal domain boundaries on function, protein stability, and folding

An N-terminally truncated and cooperatively folded version (residues 6–39) of the human Pin1 WW domain (hPin1 WW hereafter) has served as an excellent model system for understanding triple-stranded β-sheet folding energetics. Here we report that the negatively charged N-terminal sequence (Met(1)-Ala...

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Autori principali: Jäger, Marcus, Nguyen, Houbi, Dendle, Maria, Gruebele, Martin, Kelly, Jeffery W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2206688/
https://ncbi.nlm.nih.gov/pubmed/17586778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.072775507
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