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Cooperative binding of ATP and RNA induces a closed conformation in a DEAD box RNA helicase
RNA helicases couple the energy from ATP hydrolysis with structural changes of their RNA substrates. DEAD box helicases form the largest class of RNA helicases and share a helicase core comprising two RecA-like domains. An opening and closing of the interdomain cleft during RNA unwinding has been po...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2206573/ https://ncbi.nlm.nih.gov/pubmed/18184816 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0705488105 |
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