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A conformational change in the helicase core is necessary but not sufficient for RNA unwinding by the DEAD box helicase YxiN

Cooperative binding of ATP and RNA to DEAD-box helicases induces the closed conformation of their helicase core, with extensive interactions across the domain interface. The bound RNA is bent, and its distortion may constitute the first step towards RNA unwinding. To dissect the role of the conforma...

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Bibliografski detalji
Glavni autori: Karow, Anne R., Klostermeier, Dagmar
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715247/
https://ncbi.nlm.nih.gov/pubmed/19474341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp397
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