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The DNA-gate of Bacillus subtilis gyrase is predominantly in the closed conformation during the DNA supercoiling reaction

Gyrase is the only type II topoisomerase that introduces negative supercoils into DNA. Supercoiling is catalyzed via a strand-passage mechanism, in which the gate DNA (gDNA) is transiently cleaved, and a second DNA segment, the transfer DNA (tDNA), is passed through the gap before the gDNA is religa...

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Bibliografske podrobnosti
Main Authors: Gubaev, Airat, Hilbert, Manuel, Klostermeier, Dagmar
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2726392/
https://ncbi.nlm.nih.gov/pubmed/19666507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0902493106
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