Bypassing the periplasm: Reconstitution of the AcrAB multidrug efflux pump of Escherichia coli
AcrAB is a constitutively expressed, major multidrug efflux system of Escherichia coli. We have purified the cytoplasmic membrane component, AcrB, to near homogeneity, and reconstituted the protein into proteoliposomes. In the presence of ΔpH (outside acid), the protein catalyzed the extrusion of fl...
Zapisane w:
| Wydane w: | Proc Natl Acad Sci U S A |
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| Główni autorzy: | , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
National Academy of Sciences
1999
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22048/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10377390/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.13.7190 |
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