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Chimeric Analysis of AcrA Function Reveals the Importance of Its C-Terminal Domain in Its Interaction with the AcrB Multidrug Efflux Pump

AcrAB-TolC is the major, constitutively expressed efflux protein complex that provides resistance to a variety of antimicrobial agents in Escherichia coli. Previous studies showed that AcrA, a periplasmic protein of the membrane fusion protein family, could function with at least two other resistanc...

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Bibliografiske detaljer
Main Authors: Elkins, Christopher A., Nikaido, Hiroshi
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC193755/
https://ncbi.nlm.nih.gov/pubmed/12949086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.185.18.5349-5356.2003
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