A systems-biology analysis of isogenic megakaryocytic and granulocytic cultures identifies new molecular components of megakaryocytic apoptosis

BACKGROUND: The differentiation of hematopoietic stem cells into platelet-forming megakaryocytes is of fundamental importance to hemostasis. Constitutive apoptosis is an integral, yet poorly understood, facet of megakaryocytic (Mk) differentiation. Understanding Mk apoptosis could lead to advances i...

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Hlavní autoři: Chen, Chi, Fuhrken, Peter G, Huang, Li Ting, Apostolidis, Pani, Wang, Min, Paredes, Carlos J, Miller, William M, Papoutsakis, Eleftherios T
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2007
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2204013/
https://ncbi.nlm.nih.gov/pubmed/17953764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-8-384
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