A systems-biology analysis of isogenic megakaryocytic and granulocytic cultures identifies new molecular components of megakaryocytic apoptosis

BACKGROUND: The differentiation of hematopoietic stem cells into platelet-forming megakaryocytes is of fundamental importance to hemostasis. Constitutive apoptosis is an integral, yet poorly understood, facet of megakaryocytic (Mk) differentiation. Understanding Mk apoptosis could lead to advances i...

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Detalhes bibliográficos
Main Authors: Chen, Chi, Fuhrken, Peter G, Huang, Li Ting, Apostolidis, Pani, Wang, Min, Paredes, Carlos J, Miller, William M, Papoutsakis, Eleftherios T
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2204013/
https://ncbi.nlm.nih.gov/pubmed/17953764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-8-384
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