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Tumor Suppressor Protein p53 Regulates Megakaryocytic Polyploidization and Apoptosis

The molecular mechanisms underlying differentiation of hematopoietic stem cells into megakaryocytes are poorly understood. Tumor suppressor protein p53 can act as a transcription factor affecting both cell cycle control and apoptosis, and we have previously shown that p53 is activated during termina...

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Detalhes bibliográficos
Main Authors: Fuhrken, Peter G., Apostolidis, Pani A., Lindsey, Stephan, Miller, William M., Papoutsakis, Eleftherios T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2414295/
https://ncbi.nlm.nih.gov/pubmed/18397889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801923200
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