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The aryl hydrocarbon receptor (AHR) transcription factor regulates megakaryocytic polyploidization

We propose that the aryl hydrocarbon receptor (AHR) is a novel transcriptional regulator of megakaryopoietic polyploidization. Functional evidence was obtained that AHR impacts in vivo megakaryocytic differentiation and maturation; compared to wild-type mice, AHR-null mice had lower platelet counts,...

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Detalhes bibliográficos
Main Authors: Lindsey, Stephan, T. Papoutsakis, Eleftherios
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408620/
https://ncbi.nlm.nih.gov/pubmed/21226706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2141.2010.08548.x
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