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The aryl hydrocarbon receptor (AHR) transcription factor regulates megakaryocytic polyploidization
We propose that the aryl hydrocarbon receptor (AHR) is a novel transcriptional regulator of megakaryopoietic polyploidization. Functional evidence was obtained that AHR impacts in vivo megakaryocytic differentiation and maturation; compared to wild-type mice, AHR-null mice had lower platelet counts,...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3408620/ https://ncbi.nlm.nih.gov/pubmed/21226706 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2141.2010.08548.x |
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