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Bone marrow niche-inspired, multi-phase expansion of megakaryocytic progenitors with high polyploidization potential
BACKGROUND: Megakaryopoiesis encompasses hematopoietic stem and progenitor cell (HSPC) commitment to the megakaryocytic cell (Mk) lineage, expansion of Mk progenitors and mature Mks, polyploidization, and platelet release. pH and pO(2) increase from the endosteum to sinuses, and different cytokines...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3077558/ https://ncbi.nlm.nih.gov/pubmed/20482285 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/14653241003786148 |
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