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Highly penetrant myeloproliferative disease in the Ts65Dn mouse model of Down syndrome
Children with Down syndrome (DS) display macrocytosis, thrombocytosis, and a 500-fold increased risk of developing megakaryocytic leukemia; however, the specific effects of trisomy 21 on hematopoiesis remain poorly defined. To study this question, we analyzed blood cell development in the Ts65Dn mou...
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| Hoofdauteurs: | , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society of Hematology
2008
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2200841/ https://ncbi.nlm.nih.gov/pubmed/17901249 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-04-085670 |
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