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Dentate Gyrus Mediates Cognitive Function in the Ts65Dn/DnJ Mouse Model of Down Syndrome

In the Ts65Dn/DnJ mouse model of Down syndrome (DS), hippocampal deficits of learning and memory are the most robust features supporting this mouse as a valid cognitive model of DS. Although dentate gyrus (DG) dysfunction is suggested by excessive GABAergic inhibition, its role in perturbing DG func...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Hippocampus
Prif Awduron: Smith, Genevieve K., Kesner, Raymond P., Korenberg, Julie R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4480980/
https://ncbi.nlm.nih.gov/pubmed/24339224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hipo.22229
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