Early Pharmacotherapy Restores Neurogenesis and Cognitive Performance in the Ts65Dn Mouse Model for Down Syndrome

Down syndrome (DS) is a genetic pathology characterized by intellectual disability and brain hypotrophy. Widespread neurogenesis impairment characterizes the fetal and neonatal DS brain, strongly suggesting that this defect may be a major determinant of mental retardation. Our goal was to establish,...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Bianchi, Patrizia, Ciani, Elisabetta, Guidi, Sandra, Trazzi, Stefania, Felice, Daniela, Grossi, Gabriele, Fernandez, Mercedes, Giuliani, Alessandro, Calzà, Laura, Bartesaghi, Renata
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2010
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6632890/
https://ncbi.nlm.nih.gov/pubmed/20592198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0534-10.2010
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