Inhibition of tissue factor signaling suppresses tumor growth

Coagulation activation by tissue factor (TF) is implicated in cancer progression, cancer-associated thrombosis and metastasis. The role of direct TF signaling pathways in cancer, however, remains incompletely understood. Here we address how TF contributes to primary tumor growth by using a unique pa...

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Detalhes bibliográficos
Main Authors: Versteeg, Henri H., Schaffner, Florence, Kerver, Marjolein, Petersen, Helle H., Ahamed, Jasimuddin, Felding-Habermann, Brunhilde, Takada, Yoshikazu, Mueller, Barbara M., Ruf, Wolfram
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2008
Assuntos:
Hemostasis, Thrombosis, and Vascular Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2200804/
https://ncbi.nlm.nih.gov/pubmed/17901245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-07-101048
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