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Regulation of macrophage procoagulant responses by the tissue factor cytoplasmic domain in endotoxemia
Tissue factor (TF) is the primary initiator of coagulation, and the TF pathway mediates signaling through protease-activated receptors (PARs). In sepsis, TF is up-regulated as part of the proinflammatory response in lipopolysaccharide (LPS)–stimulated monocytes leading to systemic coagulation activa...
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| Main Authors: | , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society of Hematology
2007
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1890821/ https://ncbi.nlm.nih.gov/pubmed/17332247 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-10-051334 |
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