Cooperation of tissue factor cytoplasmic domain and PAR2 signaling in breast cancer development

Constitutive expression of tissue factor (TF) by cancer cells triggers local activation of the coagulation cascade and promotes breast cancer progression through cell signaling involving protease activated receptor (PAR)2. In human breast cancer, TF and PAR2 are up-regulated and TF cytoplasmic domai...

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Detalhes bibliográficos
Main Authors: Schaffner, Florence, Versteeg, Henri H., Schillert, Anja, Yokota, Naho, Petersen, Lars C., Mueller, Barbara M., Ruf, Wolfram
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2010
Assuntos:
Thrombosis and Hemostasis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3031395/
https://ncbi.nlm.nih.gov/pubmed/20861457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-06-289314
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