Cooperation of tissue factor cytoplasmic domain and PAR2 signaling in breast cancer development

Constitutive expression of tissue factor (TF) by cancer cells triggers local activation of the coagulation cascade and promotes breast cancer progression through cell signaling involving protease activated receptor (PAR)2. In human breast cancer, TF and PAR2 are up-regulated and TF cytoplasmic domai...

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Bibliographic Details
Main Authors: Schaffner, Florence, Versteeg, Henri H., Schillert, Anja, Yokota, Naho, Petersen, Lars C., Mueller, Barbara M., Ruf, Wolfram
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2010
Subjects:
Thrombosis and Hemostasis
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3031395/
https://ncbi.nlm.nih.gov/pubmed/20861457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-06-289314
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