Cooperation of tissue factor cytoplasmic domain and PAR2 signaling in breast cancer development

Constitutive expression of tissue factor (TF) by cancer cells triggers local activation of the coagulation cascade and promotes breast cancer progression through cell signaling involving protease activated receptor (PAR)2. In human breast cancer, TF and PAR2 are up-regulated and TF cytoplasmic domai...

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Bibliographische Detailangaben
Hauptverfasser: Schaffner, Florence, Versteeg, Henri H., Schillert, Anja, Yokota, Naho, Petersen, Lars C., Mueller, Barbara M., Ruf, Wolfram
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2010
Schlagworte:
Thrombosis and Hemostasis
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3031395/
https://ncbi.nlm.nih.gov/pubmed/20861457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-06-289314
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