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Role of thiol pathways in TF procoagulant regulation
The generation of procoagulant Tissue Factor (TF) is crucial for thrombosis. TF contains a surface exposed allosteric disulfide bond that stabilizes the carboxyl-terminal domain involved in ligand interactions with coagulation factors VIIa and X. TF procoagulant activation typically occurs following...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3393083/ https://ncbi.nlm.nih.gov/pubmed/22401798 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.thromres.2012.02.020 |
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