Downregulation of an Aim-1 Kinase Couples with Megakaryocytic Polyploidization of Human Hematopoietic Cells

During the late phase of megakaryopoiesis, megakaryocytes undergo polyploidization, which is characterized by DNA duplication without concomitant cell division. However, it remains unknown by which mechanisms this process occurs. AIM-1 and STK15 belong to the Aurora/increase-in-ploidy (Ipl)1 serine/...

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Detalhes bibliográficos
Main Authors: Kawasaki, Akira, Matsumura, Itaru, Miyagawa, Jun-ichiro, Ezoe, Sachiko, Tanaka, Hirokazu, Terada, Yasuhiko, Tatsuka, Masaaki, Machii, Takashi, Miyazaki, Hiroshi, Furukawa, Yusuke, Kanakura, Yuzuru
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2001
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2199624/
https://ncbi.nlm.nih.gov/pubmed/11266445
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