Involvement of Prolonged Ras Activation in Thrombopoietin-Induced Megakaryocytic Differentiation of a Human Factor-Dependent Hematopoietic Cell Line

Thrombopoietin (TPO) is a hematopoietic growth factor that plays fundamental roles is both megakaryopoiesis and thrombopoiesis through binding to its receptor, c-mpl. Although TPO has been shown to activate various types of intracellular signaling molecules, such as the Janus family of protein tyros...

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Detalhes bibliográficos
Main Authors: Matsumura, Itaru, Nakajima, Koichi, Wakao, Hiroshi, Hattori, Seisuke, Hashimoto, Koji, Sugahara, Hiroyuki, Kato, Takashi, Miyazaki, Hiroshi, Hirano, Toshio, Kanakura, Yuzuru
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC109012/
https://ncbi.nlm.nih.gov/pubmed/9632812
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