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Control of thrombopoietin-induced megakaryocytic differentiation by the mitogen-activated protein kinase pathway.

Thrombopoietin (TPO) is the major regulator of both growth and differentiation of megakaryocytes. We previously showed that both functions can be generated by TPO in the megakaryoblastic cell line UT7, in which murine Mpl was introduced, and are independently controlled by distinct regions of the cy...

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Bibliographic Details
Main Authors: Rouyez, M C, Boucheron, C, Gisselbrecht, S, Dusanter-Fourt, I, Porteu, F
Format: Artigo
Language:Inglês
Published: 1997
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC232350/
https://ncbi.nlm.nih.gov/pubmed/9271377
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